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| Status |
Public on Jul 01, 2012 |
| Title |
Analysis of gene expression change by gefitinib treatment in gefitinib sensitive PC9 and resistant PC9. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
We established a gefitinib-resistant cell line (PC-9GR), by serial exposure of gefitinib to PC-9, an originally gefitinib-sensitive lung cancer cell line (PC-9na), for long period.We collected total RNA from both PC-9 and PC-9GR and examined mRNA expression profile, comprehensively.
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| Overall design |
Gefitinib induced gene expression was measured in human lung cancer cell line was measured at 48 hours after exposure to 1uM Gefitinib.
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| Contributor(s) |
Terai H, Soejima K, Hamamoto J |
| Citation(s) |
23536707 |
| Submission date |
May 29, 2012 |
| Last update date |
Nov 27, 2018 |
| Contact name |
Junko Hamamoto |
| E-mail(s) |
junko_hamamoto@a7.keio.jp
|
| Organization name |
School of Medicine, Keio University
|
| Department |
Pulmonary Medicine
|
| Street address |
35 Shinanomachi, Shinjuku-ku
|
| City |
Tokyo |
| ZIP/Postal code |
160-8582 |
| Country |
Japan |
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| Platforms (1) |
| GPL13607 |
Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Feature Number version) |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA167833 |
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