GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE3807 Query DataSets for GSE3807
Status Public on Dec 26, 2005
Title CD3+ T cells derived from bone marrow or peripheral blood of aplastic anemia patients
Organism Homo sapiens
Experiment type Expression profiling by array
Summary CD3+ T cells derived from bone marrow aspirates and peripheral blood samples of newly diagnosed AA patients and healthy volunteers were analysed using Affymetrix HG_U133A GeneChips. Additionally, two patients were studied after achieving a partial remission (post-Therapy).
Keywords: disease vs health vs response to therapy
Overall design Altogether, we analysed 8 different samples. Pool I contained three female and one male patients, 19 to 70 years old, suffering from (severe) aplastic anemia. From these four donors, samples derived from bone marrow aspirates and from peripheral blood, were pooled on total-RNA basis. Pool II consisted of additional two patients, one male (64 years old) and one female (70 years old). From both donors, total-RNA was extracted and pooled from CD3+ T cells derived either from bone marrow or peripheral blood, each prior and post therapy. Healthy control pools included three donors for the peripheral blood sample and two donors for bone marrow derived T cells.
Citation(s) 17052335
Submission date Dec 12, 2005
Last update date Aug 29, 2019
Contact name Susanne Pfoertner
Organization name German Research Centre for Biotechnology (GBF)
Street address Mascheroder Weg 1
City Braunschweig
ZIP/Postal code 38124
Country Germany
Platforms (1)
GPL96 [HG-U133A] Affymetrix Human Genome U133A Array
Samples (8)
GSM87341 BM_preTherapy_IIa
GSM87342 BM_postTherapy_IIb
GSM87343 PB_preTherapy_IIa
BioProject PRJNA94009

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary data files not provided

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap