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Series GSE37726 Query DataSets for GSE37726
Status Public on May 08, 2012
Title A novel miRNA produced during lytic HSV-1 infection is important for efficient replication in tissue culture.
Organism Homo sapiens
Experiment type Non-coding RNA profiling by high throughput sequencing
Summary We report a HSV-1 encoded miRNA present during lytic infection that influences replication efficiency in a tissue culture model. miRNAs were identified using high-throughput sequencing of HSV-1 infected epithelial cells. Functional assays were performed by mutating the miRNA coding region and testing grow of the mutant in vitro.
Overall design Construction of a miRNA library and sequencing to reveal novel viral miRNAs from lytically infected cells
Contributor(s) Munson DJ, Burch AD
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Submission date May 02, 2012
Last update date May 15, 2019
Contact name April D Burch
Organization name Wadsworth Center/ SUNY Albany/ Berkshire School
Department Infectious Diseases
Lab Burch Lab
Street address 120 New Scotlant Ave
City Albany
State/province NY
ZIP/Postal code 12208
Country USA
Platforms (1)
GPL10999 Illumina Genome Analyzer IIx (Homo sapiens)
Samples (1)
GSM926147 HEK293 HSV-1 infected
BioProject PRJNA162879
SRA SRP012612

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Supplementary file Size Download File type/resource
GSE37726_RAW.tar 120.0 Kb (http)(custom) TAR (of PDF)
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Processed data provided as supplementary file
Raw data are available in SRA

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