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Series GSE37709 Query DataSets for GSE37709
Status Public on Oct 01, 2013
Title HIF1alpha drives early induction of pluripotency through reprogramming of glycolytic metabolism
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Gene expression analyis of two neonatal fibroblasts (BJ and HFF1), one adult dermal fibroblasts (NFH2), two BJ-derived human iPSCs (iB4 and iB5), two HFF1-derived iPSCs (iPS 2 and iPS4), four NFH2-derived iPSCs (OiPS3, OiPS6, OiPS8, OiPS16), one amniotic fluid cells and three derived iPSCs (lines 4, 5, 6, 10, and 41), two human ES cells (H1 and H9), neonatal fibroblasts transduced with the four retroviral factors (OKSM) after 24h, 48h, and 72h, neonatal fibroblasts treated with EDHB for 24h, 48h, and 72h, neonatal fibroblasts transduced with four factors and treated with EDHB for 24h, 48h, and 72h, neonatal fibroblasts knocked down for HIF1A (HIF1-KD) and for a scrambled sequence (SCR-KD)
 
Overall design Total mRNA obtained from somatic cells (fibroblasts and amniotic fluid cells), pluripotent stem cells (iPSCs and hESCs), and somatic cells exposed to HIF1A activation or HIF1A suppsression in addition to the standard retroviral-based reprogramming.
 
Contributor(s) Prigione A
Citation(s) 24123565
Submission date May 02, 2012
Last update date Mar 20, 2017
Contact name Alessandro Prigione
E-mail(s) alessandro.prigione@mdc-berlin.de
Organization name Max Delbrueck Center for Molecular Medicine
Lab Department of Neuroproteomics
Street address Robert-Roessle-Str. 10
City Berlin
State/province Berlin
ZIP/Postal code D-13125
Country Germany
 
Platforms (1)
GPL6883 Illumina HumanRef-8 v3.0 expression beadchip
Samples (48)
GSM653295 BJ-a
GSM653296 BJ-b
GSM653297 HFF1-a
Relations
BioProject PRJNA162867

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE37709_RAW.tar 3.9 Mb (http)(custom) TAR
GSE37709_non-normalized_data.txt.gz 4.9 Mb (ftp)(http) TXT
Processed data included within Sample table

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