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Series GSE37646 Query DataSets for GSE37646
Status Public on May 02, 2012
Title Distinct STAT5 concentrations uniquely control establishment and differentiation of mammary epithelium during pregnancy
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary To dissect regulatory processes of cell proliferation and differentiation we generated mouse strains carrying any combination of the four Stat5 alleles, thus expressing STAT5 from 0 to 100%. RNA-Seq analyses revealed that different STAT5 levels activate specific genetic programs linked to cell proliferation and differentiation.
Overall design We refer to wild-type mice and Stat5abfl/fl mice as AABB mice; Stat5abfl/fl;MMTV-Cre (with Stat5ab-deficient mammary epithelial cells) as Null mice; Stat5a-/- mice as BB mice; Stat5b-/- mice as AA mice; Stat5ab+/null mice as AB mice.
Contributor(s) Daisuke Y, Keunsoo K, Gertraud RW, Lothar H
Citation(s) 23275557
Submission date Apr 29, 2012
Last update date May 15, 2019
Contact name Keunsoo Kang
Phone 82-41-550-3456
Organization name Dankook University
Department Microbiology
Lab Computational Biology Lab
Street address Dandae-ro 119
City Cheonan
State/province Chungnam
ZIP/Postal code 31116
Country South Korea
Platforms (1)
GPL13112 Illumina HiSeq 2000 (Mus musculus)
Samples (31)
GSM924996 Stat5-null rep1 in P6
GSM924997 Stat5-null rep2 in P6
GSM924998 Stat5-null rep3 in P6
SRA SRP012574
BioProject PRJNA162891

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SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE37646_Yamaji_L1_FPKM.txt.gz 613.5 Kb (ftp)(http) TXT
GSE37646_Yamaji_P6_FPKM.txt.gz 665.6 Kb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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