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| Status |
Public on Oct 03, 2013 |
| Title |
Genome-wide gene expression during osteogenic and myogenic differentiation from adipose- derived stem cells. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
In the current study, we have performed a gene expression analysis of well characterized and defined populations of human adipose-derived stem cells (hASCs) before and after in vitro induction of osteogenic and myogenic differentiation that allows identifying DNA methylation- regulated differentiation genes. We have also address the extent of the epigenetic programming of hASCs- derived differentiated cells by comparing the expression profiling of these cells with their somatic counterparts from primary tissues. Finally, we also compared the patterns of expression of hASCs (and their derivatives)
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| |
|
| Overall design |
Identify all genes or probe-sets whose expression was significantly different between control hASCs and each one of the two differentiated cell types (DIF.M and DIF.O),
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| |
|
| Contributor(s) |
Esteller M, Berdasco M |
| Citation(s) |
23031258 |
| |
| Submission date |
Apr 17, 2012 |
| Last update date |
Nov 08, 2016 |
| Contact name |
Manel Esteller |
| Organization name |
IDIBELL
|
| Department |
PEBC
|
| Lab |
Cancer Epigenetics
|
| Street address |
Hospital Duran i Reynals Av. Gran Via s/n km, 2.7
|
| City |
L'Hospitalet de Llobregat |
| State/province |
Barcelona |
| ZIP/Postal code |
08908 |
| Country |
Spain |
| |
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| Platforms (1) |
| GPL11532 |
[HuGene-1_1-st] Affymetrix Human Gene 1.1 ST Array [transcript (gene) version] |
|
| Samples (7)
|
| GSM916203 |
adipose- derived stem cells Donor 1 |
| GSM916204 |
adipose- derived stem cells Donor 2 |
| GSM916205 |
adipose- derived stem cells Donor 3 |
| GSM916206 |
in vitro induced osteocytes (donor 1) |
| GSM916207 |
in vitro induced osteocytes (donor 2) |
| GSM916208 |
in vitro induced myocytes (donor 1) |
| GSM916209 |
in vitro induced myocytes (donor 2) |
|
| Relations |
| BioProject |
PRJNA159585 |
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