|
Status |
Public on Mar 09, 2012 |
Title |
Rev-erb(alpha) and (beta) Coordinately Protect the Circadian Clock and Normal Metabolic Function |
Organism |
Mus musculus |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing Third-party reanalysis
|
Summary |
We report the genomic regions enriched for Rev-erb(beta) binding in WT mouse liver, in addition to the false positive regions enriched by ChIP for Rev-erb(alpha) in Rev-erb(alpha) KO liver. In conjunction with previously published data for Rev-erb(alpha) in GSE26345 (GSM647029, GSM647033, and GSM647034), we report the common and subtype specific cistromes for Rev-erb using a quantitative analysis method.
|
|
|
Overall design |
Rev-erb(beta) ChIP-seq in liver from WT mice at 5AM/ZT22 and 5PM/ZT10, and Rev-erb(alpha) ChIP-seq in liver from Rev-erb(alpha) KO mice at 5PM/ZT10.
|
|
|
Contributor(s) |
Bugge A, Feng D, Everett LJ, Briggs ER, Mullican SE, Wang F, Jager J, Lazar MA |
Citation(s) |
22474260, 21393543 |
Submission date |
Mar 08, 2012 |
Last update date |
May 15, 2019 |
Contact name |
Logan J Everett |
Organization name |
U.S. Environmental Protection Agency
|
Department |
Office of Research and Development
|
Lab |
Center for Computational Toxicology and Exposure
|
Street address |
109 T.W. Alexander Dr
|
City |
RTP |
State/province |
North Carolina |
ZIP/Postal code |
27711 |
Country |
USA |
|
|
Platforms (2) |
GPL11002 |
Illumina Genome Analyzer IIx (Mus musculus) |
GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
|
Samples (3) |
|
Relations |
Reanalysis of |
GSM647029 |
Reanalysis of |
GSM647033 |
Reanalysis of |
GSM647034 |
SRA |
SRP011388 |
BioProject |
PRJNA153253 |