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Series GSE36375 Query DataSets for GSE36375
Status Public on Mar 09, 2012
Title Rev-erb(alpha) and (beta) Coordinately Protect the Circadian Clock and Normal Metabolic Function
Organism Mus musculus
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Third-party reanalysis
Summary We report the genomic regions enriched for Rev-erb(beta) binding in WT mouse liver, in addition to the false positive regions enriched by ChIP for Rev-erb(alpha) in Rev-erb(alpha) KO liver. In conjunction with previously published data for Rev-erb(alpha) in GSE26345 (GSM647029, GSM647033, and GSM647034), we report the common and subtype specific cistromes for Rev-erb using a quantitative analysis method.
 
Overall design Rev-erb(beta) ChIP-seq in liver from WT mice at 5AM/ZT22 and 5PM/ZT10, and Rev-erb(alpha) ChIP-seq in liver from Rev-erb(alpha) KO mice at 5PM/ZT10.
 
Contributor(s) Bugge A, Feng D, Everett LJ, Briggs ER, Mullican SE, Wang F, Jager J, Lazar MA
Citation(s) 22474260, 21393543
Submission date Mar 08, 2012
Last update date May 15, 2019
Contact name Logan J Everett
Organization name U.S. Environmental Protection Agency
Department Office of Research and Development
Lab Center for Computational Toxicology and Exposure
Street address 109 T.W. Alexander Dr
City RTP
State/province North Carolina
ZIP/Postal code 27711
Country USA
 
Platforms (2)
GPL11002 Illumina Genome Analyzer IIx (Mus musculus)
GPL13112 Illumina HiSeq 2000 (Mus musculus)
Samples (3)
GSM890125 Reverb_beta_5pm
GSM890126 Reverb_beta_5am
GSM890127 Reverb_alpha_null_5pm
Relations
Reanalysis of GSM647029
Reanalysis of GSM647033
Reanalysis of GSM647034
SRA SRP011388
BioProject PRJNA153253

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE36375_RAW.tar 1.6 Gb (http)(custom) TAR (of BED)
GSE36375_ReverbAlpha_Liver_ZT10_homer_noKO.bed.gz 326.4 Kb (ftp)(http) BED
GSE36375_Reverb_cistrome_alpha_specific.bed.gz 24.0 Kb (ftp)(http) BED
GSE36375_Reverb_cistrome_beta_specific.bed.gz 13.4 Kb (ftp)(http) BED
GSE36375_Reverb_cistrome_common.bed.gz 495.9 Kb (ftp)(http) BED
GSE36375_readme.txt 1.9 Kb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file
Processed data are available on Series record

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