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Series GSE36041 Query DataSets for GSE36041
Status Public on Feb 25, 2012
Title Impaired Insulin-/IGF1-Signaling Extends Life Span by Promoting Mitochondrial L-Proline Catabolism to Induce a Transient ROS-Signal
Organisms Caenorhabditis elegans; Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Transcriptome profiling of three models with impaired insulin/IGF1 signaling. 1. Deep sequencing of endogenous mRNA from Caenorhabditis elegans N2 var. Bristol (wildtype) and daf-2(e1370) mutant; 2. Deep sequencing of endogenous mRNA from murine embryonic fibroblasts (MEF) wildtype and irs1-/- knockout; 3. Deep sequencing of endogenous mRNA from murine embryoinic fibroblast (MEF) insr+/- -lox and insr+/- knockout

Jena Centre for Systems Biology of Ageing - JenAge (
Overall design 14 samples examined: C. elegans N2 var. Bristol (wildtype) vs. daf-2(e1370) mutant; MEF wildtype vs. irs1-/- knockout; MEF insr+/- -lox vs. insr +/- knockout
Contributor(s) Zarse K, Ristow M, Groth M, Priebe S
Citation(s) 22482728
Submission date Feb 23, 2012
Last update date May 15, 2019
Contact name JenAge Project
Organization name Leibniz Institute for Age Research - Fritz Lipmann Institute
Street address Beutenbergstr. 11
City Jena
ZIP/Postal code D-07745
Country Germany
Platforms (2)
GPL11002 Illumina Genome Analyzer IIx (Mus musculus)
GPL13776 Illumina Genome Analyzer IIx (Caenorhabditis elegans)
Samples (14)
GSM879792 Endogenous mRNA from N2 var. Bristol (wildtype) 1
GSM879793 Endogenous mRNA from daf-2(e1370) mutant 1
GSM879794 Endogenous mRNA from N2 var. Bristol (wildtype) 2
SRA SRP011038
BioProject PRJNA151765

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE36041_GSM879792-GSM879797_ce_Sample1-6_gene_counts.csv.gz 395.9 Kb (ftp)(http) CSV
GSE36041_GSM879792-GSM879797_ce_Sample1-6_transcript_counts.csv.gz 410.5 Kb (ftp)(http) CSV
GSE36041_GSM879798-GSM879801_MEF_Sample7-10_gene_counts.csv.gz 401.4 Kb (ftp)(http) CSV
GSE36041_GSM879798-GSM879801_MEF_Sample7-10_transcript_counts.csv.gz 366.4 Kb (ftp)(http) CSV
GSE36041_GSM879802-GSM879805_MEF_Sample11-14_gene_counts.csv.gz 271.0 Kb (ftp)(http) CSV
GSE36041_GSM879802-GSM879805_MEF_Sample11-14_transcript_counts.csv.gz 240.6 Kb (ftp)(http) CSV
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