|
| Status |
Public on Nov 11, 2006 |
| Title |
Lentiviral gene delivery of vMIP-II |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
We engineered a lentiviral gene vector with vMIP-II, transduced both mature endothelial cells and endothelial cell progenitors, and transplanted these gene-modified cells in Matrigel templates as an in vivo angiogenesis model. The results are the first demonstration in a cell transplantation setting that vMIP-II is proangiogenic in vivo and can deliver this function by vector-mediated gene delivery to both mature endothelial cells and progenitors.
Keywords: Comparative Genomic Hybridisations
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| |
|
| Overall design |
5 samples in total, hybridised to Affymetrix HG-U133A 2.0 GeneChips, comprising 3 HUVEC control samples and 2 HUVEC experimental samples transduced with vMIP-II.
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| |
|
| Contributor(s) |
Cherqui S, Thorpe C, Kurian SM, Salomon DR |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Nov 11, 2005 |
| Last update date |
Dec 06, 2018 |
| Contact name |
Sunil Kurian |
| E-mail(s) |
smkurian@scripps.edu
|
| Phone |
858-784-7759
|
| Organization name |
The Scripps Research Institute
|
| Department |
Molecular and Experimental Medicine
|
| Street address |
10550 N Torrey Pines Road
|
| City |
La Jolla |
| State/province |
CA |
| ZIP/Postal code |
92037 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL571 |
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array |
|
| Samples (5)
|
| GSM83096 |
HUVEC cells transduced with vMIP-II 1 |
| GSM83097 |
HUVEC cells transduced with vMIP-II 2 |
|
| Relations |
| BioProject |
PRJNA93703 |
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