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Series GSE36005 Query DataSets for GSE36005
Status Public on Aug 21, 2012
Title High throughput sequencing of the mouse transcriptome within the VTA following exposure to emotional stress.
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Using a novel stress paradigm, we generated emotionally stressed, physically stressed, and control animals. We measured changes in mRNA expression using Illumina HiSeq2000 to obtain high-depth sequencing. Interestingly, we observed a number of significantly up- and down-regulated mRNAs. By identifying mRNAs that were regulated similarly in both emotionally and physically stressed mice, we hope to provide a list of potentially novel targets for therapeutic intervention in mood disorder.
Overall design Examination of the transcriptome within the VTA in emotionally and physically (both susceptible and resilient) stressed C57BL/6J male mice.
Contributor(s) Warren B, Shen L, Vialou V, Bolanos-Guzman C
Citation(s) 22795644
Submission date Feb 22, 2012
Last update date May 15, 2019
Contact name Li Shen
Organization name Icahn School of Medicine at Mount Sinai
Department Neuroscience
Lab Shen
Street address 1425 Madison Ave
City New York
State/province NY
ZIP/Postal code 10029
Country USA
Platforms (1)
GPL13112 Illumina HiSeq 2000 (Mus musculus)
Samples (12)
GSM879225 Control R1
GSM879226 Control R2
GSM879227 Control R3
SRA SRP011014
BioProject PRJNA151701

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE36005_RAW.tar 12.8 Mb (http)(custom) TAR (of FPKM_TRACKING)
GSE36005_emo_gene.diff.gz 1.3 Mb (ftp)(http) DIFF
GSE36005_res_gene.diff.gz 1.3 Mb (ftp)(http) DIFF
GSE36005_sus_gene.diff.gz 1.3 Mb (ftp)(http) DIFF
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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