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Status |
Public on Feb 05, 2012 |
Title |
Trans Chromosomal Methylation in Arabidopsis hybrids |
Organism |
Arabidopsis thaliana |
Experiment type |
Methylation profiling by high throughput sequencing
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Summary |
The heterotic hybrid offspring of Arabidopsis accessions C24 and Landsberg erecta have altered methylomes. Changes occur most frequently at loci where parental methylation levels are different. There are context-specific biases in the non-additive methylation patterns with mCG generally increased and mCHH decreased relative to the parents. These changes are a result of two main mechanisms, Trans Chromosomal Methylation (TCM) and Trans Chromosomal deMethylation (TCdM), where the methylation level of one parental allele alters to resemble that of the other parent. Regions of altered methylation are enriched around genic regions and are often correlated with changes in siRNA levels. We identified examples of genes with altered expression likely to be due to methylation changes and suggest that in crosses between the C24 and Ler accessions, epigenetic controls can be important in the generation of altered transcription levels which may contribute to the increased biomass of the hybrids.
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Overall design |
C24, Ler, and C24 x Ler
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Contributor(s) |
Greaves IK |
Citation(s) |
22331882 |
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Submission date |
Feb 03, 2012 |
Last update date |
May 15, 2019 |
Contact name |
Jennifer Taylor |
E-mail(s) |
jen.taylor@csiro.au
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Organization name |
CSIRO
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Department |
Plant Industry
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Street address |
Clunies Ross St
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City |
Canberra |
ZIP/Postal code |
2601 |
Country |
Australia |
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Platforms (1) |
GPL11221 |
Illumina Genome Analyzer IIx (Arabidopsis thaliana) |
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Samples (4)
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Relations |
SRA |
SRP010749 |
BioProject |
PRJNA152271 |
Supplementary file |
Size |
Download |
File type/resource |
GSE35542_RAW.tar |
8.2 Gb |
(http)(custom) |
TAR (of BSP) |
GSE35542_README_BSMAP_Format.txt |
838 b |
(ftp)(http) |
TXT |
SRA Run Selector |
Raw data are available in SRA |
Processed data provided as supplementary file |
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