NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Series GSE35542 Query DataSets for GSE35542
Status Public on Feb 05, 2012
Title Trans Chromosomal Methylation in Arabidopsis hybrids
Organism Arabidopsis thaliana
Experiment type Methylation profiling by high throughput sequencing
Summary The heterotic hybrid offspring of Arabidopsis accessions C24 and Landsberg erecta have altered methylomes. Changes occur most frequently at loci where parental methylation levels are different. There are context-specific biases in the non-additive methylation patterns with mCG generally increased and mCHH decreased relative to the parents. These changes are a result of two main mechanisms, Trans Chromosomal Methylation (TCM) and Trans Chromosomal deMethylation (TCdM), where the methylation level of one parental allele alters to resemble that of the other parent. Regions of altered methylation are enriched around genic regions and are often correlated with changes in siRNA levels. We identified examples of genes with altered expression likely to be due to methylation changes and suggest that in crosses between the C24 and Ler accessions, epigenetic controls can be important in the generation of altered transcription levels which may contribute to the increased biomass of the hybrids.
 
Overall design C24, Ler, and C24 x Ler
 
Contributor(s) Greaves IK
Citation(s) 22331882
Submission date Feb 03, 2012
Last update date May 15, 2019
Contact name Jennifer Taylor
E-mail(s) jen.taylor@csiro.au
Organization name CSIRO
Department Plant Industry
Street address Clunies Ross St
City Canberra
ZIP/Postal code 2601
Country Australia
 
Platforms (1)
GPL11221 Illumina Genome Analyzer IIx (Arabidopsis thaliana)
Samples (4)
GSM870347 C24 methylC
GSM870348 Ler methylC
GSM870349 C24 x Ler methylC
Relations
SRA SRP010749
BioProject PRJNA152271

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE35542_RAW.tar 8.2 Gb (http)(custom) TAR (of BSP)
GSE35542_README_BSMAP_Format.txt 838 b (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap