GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE34989 Query DataSets for GSE34989
Status Public on May 31, 2014
Title A high-throughput screen to study the role of stem cells in hemangioma tumor formation
Organism Homo sapiens
Experiment type Expression profiling by array
Summary To further the development of gene expression signatures for infantile hemangioma (IH) cells, gene expression analysis was performed of different human cell samples using Agilent whole human genome oligo microarrays. The purpose of the experiments are: a) to identify the intrinsic differences between HemSc and HemDerivatives and compare HemSc and HemDerivatives genetically; b) analyze the "stemness" genes, paracrine/endocrine associated genes ("angiocrine"), and genes that regulate development, vasculogenesis and immunity; c) identify involvement of the signaling pathways at various stages of differentiation; and d) provide new perspectives on the failure of anti-vasculogenic inhibitors currently in use.
Overall design Expression Profiles: To employ whole human genome gene expression analysis of infantile hemangioma cells by using microarray analysis followed by qPCR and microfluidic single cell analysis to: a) survey gene expression profiles and patterns between HemSc and HemDerivatives and compare HemSc and HemDerivatives genetically; Survey gene expression profiles and patterns between different populations of infantile hemangioma cells and Controls (including HemSC, Hem-Heterogeneous, HemDerivatives, BMSC, MSC, CBSC, HUVEC, and Glioblastoma CSC populations).
Contributor(s) Harbi S
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Jan 10, 2012
Last update date Nov 27, 2018
Contact name Shaghayegh Harbi
Organization name New York University
Street address -
City New York
ZIP/Postal code 10010
Country USA
Platforms (1)
GPL13607 Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Feature Number version)
Samples (34)
GSM1395123 HEM-1
GSM1395124 HEM-2
GSM1395125 HEM-3
BioProject PRJNA151091

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE34989_RAW.tar 420.3 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap