|
| Status |
Public on Oct 06, 2005 |
| Title |
Dosage Compensation of the Active X in mammals |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Here, we show that doubling of the global expression level of the X chromosome achieves dosage compensation in somatic tissues from several mammalian species. X-linked genes are highly expressed in brain tissues, consistent with a role in cognitive functions.
Keywords: Normal Tissue
|
| |
|
| Overall design |
Eight arrays were acquired from Affymetrix. Total gender-specific RNA was purchased from Stratagene. Probe labeling, array hybridization and scanning were done by the University of Washington Microarray Center (TUhttp://ra.microslu.washington.edu/UT). cDNA arrays.
|
| |
|
| Contributor(s) |
Nguyen DK, Disteche CM |
| Citation(s) |
16341221 |
| Submission date |
Oct 04, 2005 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Di Kim Nguyen |
| E-mail(s) |
dknguyen@u.washington.edu
|
| Phone |
206-685-2801
|
| Organization name |
University of Washington
|
| Department |
Pathology
|
| Lab |
Christine Disteche
|
| Street address |
1959 NE Pacific St.
|
| City |
Seattle |
| State/province |
WA |
| ZIP/Postal code |
98012 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
|
| Samples (8)
|
|
| Relations |
| BioProject |
PRJNA93437 |
Less...
More...