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| Status |
Public on Dec 27, 2011 |
| Title |
Extensive genetic diversity and substructuring among zebrafish strains revealed through copy number variant analysis (CGH) |
| Organism |
Danio rerio |
| Experiment type |
Genome variation profiling by genome tiling array
|
| Summary |
Copy number variants (CNVs) represent a substantial source of genomic variation in vertebrates, but the zebrafish reference genome has no annotated CNV information. We further analyzed zebrafish CNVs using pooled samples of 10 zebrafish each from three laboratory strains (AB, Tubingen, and WIK) to identify strain specific CNVs between groups.
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| Overall design |
10 zebrafish from 3 laboratory strains were pooled and run against the other pooled samples resulting in three array combinations.
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| Contributor(s) |
Brown KH, Dobrinski KP, Lee AS, Gokcumen O, Mills RE, Shi X, Chong WW, Chen JH, David S, Yoo P, Peterson SM, Raj T, Choy KW, Stranger B, Williamson RE, Zon LI, Freeman JL, Lee C |
| Citation(s) |
22203992 |
| |
| Submission date |
Nov 27, 2011 |
| Last update date |
Mar 23, 2012 |
| Contact name |
Charles Lee |
| E-mail(s) |
clee@rics.bwh.harvard.edu
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| Organization name |
Brigham and Women's Hospital/Harvard Medical School
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| Department |
Pathology
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| Lab |
Lee Lab--Molecular Genetic Research Unit
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| Street address |
221 Longwood Ave., EBRC-422
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| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02115 |
| Country |
USA |
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| Platforms (1) |
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| Samples (3) |
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| This SubSeries is part of SuperSeries: |
| GSE28328 |
Extensive genetic diversity and substructuring among zebrafish strains revealed through copy number variant analysis |
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| Relations |
| BioProject |
PRJNA150531 |
