|
| Status |
Public on Dec 01, 2013 |
| Title |
A functional map of DNA-associated proteolysis |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We established an assay to localize DNA-associated proteins that are slated for degradation by the ubiquitin-proteasome system. The genome-wide map we describe here ties proteolysis to active enhancer elements and to transcription start sites of specific gene families.
|
| |
|
| Overall design |
ChIP-sequencing of ubiquitin and transcription factors was performed in the presence or absence of proteasome inhibition.
|
| |
|
| Contributor(s) |
Catic A |
| Citation(s) |
24315104 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| K01 AG036744 |
Regulation of stem cell fate by protein degradation |
BAYLOR COLLEGE OF MEDICINE |
Catic |
|
| Submission date |
Nov 18, 2011 |
| Last update date |
May 15, 2019 |
| Contact name |
Andre Catic |
| E-mail(s) |
catic@post.harvard.edu
|
| Organization name |
Baylor College of Medicine
|
| Street address |
One Baylor Plaza
|
| City |
Houston |
| State/province |
TX |
| ZIP/Postal code |
77030 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
|
| Samples (12)
|
|
| Relations |
| SRA |
SRP009613 |
| BioProject |
PRJNA148047 |
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