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Series GSE33721 Query DataSets for GSE33721
Status Public on Dec 13, 2011
Title Mouse peritoneal macrophages at 3.5 or 48 hours, 0,0.5 or 5 μg/ml Leukocyte cell-derived chemotaxin 2 (LECT2),gene expression array, two independent biological replicates
Organism Mus musculus
Experiment type Expression profiling by array
Summary LECT2 is a liver derived cytokine and involved in many pathologic conditions, especially in immune regulation. To better understand cellular and molecular mechanisms of LECT2 in immune response, mouse peritoneal macrophages were isolated from mouse peritonaeum. After treatment with 0, 0.5 or 5 μg/ml of LECT2 for 3.5 or 48 hours, gene expression profile in mouse peritoneal macrophages was measured using gene expression array. Results showed that LECT2 treatment led to the enhancement of cytokines secretion and phagocytosis in peritoneal macrophages.
 
Overall design Gene expression in mouse peritoneal macrophages isolated from mouse peritonaeum were measured after exposure to 0,0.5 or 5 μg/ml LECT2 for 3.5 or 48 hours using gene expression array. Two independent experiments were performed using different mice for each experiment for gene expression array analysis.
 
Contributor(s) Chen J, Lu X, Shi Y, Zhang R, Lv J, Huang Z
Citation(s) 23254286
Submission date Nov 15, 2011
Last update date Nov 01, 2017
Contact name wang liang
E-mail(s) wangliangkexue@163.com
Organization name BioChainBJ
Street address 7A North Yongchang Road BDA
City Beijing
ZIP/Postal code 100176
Country China
 
Platforms (1)
GPL11202 Agilent-026655 Whole Mouse Genome Microarray 4x44K v2 (Probe Name version)
Samples (8)
GSM833350 Low dosage of LECT2 vs control, 3.5 hours, biological replicate 1 of 2
GSM833351 High dosage of LECT2 vs control, 3.5 hours, biological replicate 1 of 2
GSM833352 Low dosage of LECT2 vs control, 48 hours, biological replicate 1 of 2
Relations
BioProject PRJNA148451

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE33721_RAW.tar 34.3 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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