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Series GSE32364 Query DataSets for GSE32364
Status Public on Apr 06, 2012
Title Murine blood monocyte subsets
Organism Mus musculus
Experiment type Expression profiling by array
Summary Monocytes and their lineage descendants serve as a central defense system against infection and injury but if uncontrolled can also promote an excessive pathological inflammatory response. Therefore a current research goal is to understand how the organism controls the number and function of monocytes and how these variables can be tailored in therapy. Considering the evidence that monocytes are heterogeneous and exist in at least two subsets committed to divergent functions, we investigated whether distinct factors regulate the balance between monocyte subset responses in vivo. Here we investigate the differential expression of mRNA among murine steady-state monocyte subsets.
Overall design Blood was drawn from healthy C57BL/6 donors. For each biological replicate 1000 monocytes of the Ly-6Chi and Ly-6Clo phenotype were isolated from the blood sample through fluorescence activated cell sorting.
Contributor(s) Etzrodt M
Citation(s) 22545247
Submission date Sep 24, 2011
Last update date Jan 12, 2017
Contact name Martin Etzrodt
Phone (617) 643-0500
Fax (617) 643-6133
Organization name Massachusetts General Hospital
Department Center for Systems Biology
Lab Pittet Lab
Street address 185 Cambridge Street
City Boston
State/province MA
ZIP/Postal code 02114
Country USA
Platforms (1)
GPL7202 Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Probe Name version)
Samples (8)
GSM371664 Monocyte_Ly6Chi_Blood_01
GSM371667 Monocyte_Ly6Chi_Blood_02
GSM371669 Monocyte_Ly6Chi_Blood_03
This SubSeries is part of SuperSeries:
GSE32392 Regulation of Monocyte Functional Heterogeneity by miR-146a
BioProject PRJNA154529

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE32364_RAW.tar 72.9 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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