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Series GSE32280 Query DataSets for GSE32280
Status Public on Mar 21, 2012
Title Expression data from peripheral blood lymphocytes of major depression, subsyndromal symptomatic depression, and healthy controls
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Several studies have suggested that SSD is a transitory phenomena in the depression spectrum and is thus considered a subtype of depression. However, the pathophysioloy of depression remain largely obscure and studies on SSD are limited. The present study compared the expression profile and made the classification with the leukocytes by using whole-genome cRNA microarrays among drug-free first-episode subjects with SSD, MDD, and healthy controls.
We used microarrays to detail the global programme of gene expression to develop blood-based gene expression profiles models for classification of subsyndromal symptomatic depression and major depressive disorder
 
Overall design The present study compared the expression profile and made the classification with the leukocytes by using whole-genome cRNA microarrays among drug-free first-episode subjects with SSD, MDD, and matched controls (8 subjects in each group). Support vector machines (SVMs) were utilized for training and testing on candidate signature expression profiles from signature selection step.
 
Contributor(s) Yi Z, Li Z
Citation(s) 22348066
Submission date Sep 21, 2011
Last update date Aug 16, 2019
Contact name Zezhi Li
E-mail(s) lizezhi1981@yahoo.cn
Phone +86 13564648631
Organization name Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Department Division of Mood Disorders
Street address 600 South Wan Ping Road Shanghai 200030, China
City Shanghai
ZIP/Postal code 200030
Country China
 
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (37)
GSM799722 MDD patient 3 before treatment
GSM799723 MDD patient 4 before treatment
GSM799724 MDD patient 1 before treatment
Relations
BioProject PRJNA146347

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE32280_RAW.tar 156.2 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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