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Series GSE32146 Query DataSets for GSE32146
Status Public on Jun 01, 2013
Title DNA methylation in a discovery cohort of colon mucosa samples from individuals with Crohns' disease or ulcerative colitis and normal controls
Organism Homo sapiens
Experiment type Methylation profiling by genome tiling array
Summary Genome wide DNA methylation profiling of Crohn's disease, ulcerative colitis, and normal colon mucosa samples. The Illumina Infinium HumanMethylation450 BeadChip v1.1 was used to obtain DNA methylation profiles across 482,421 CpGs in colon mucosa samples. Samples came from 10 Crohn's disease affected, 4 ulcerative colitis affected, and 10 normal individuals. One ulcerative colitis sample was assayed before and after treatment with 6-mercaptopurine and mesalamine.
 
Overall design Bisulfite converted DNA from the 25 samples were hybridized to the Illumina Infinium HumanMethylation450 BeadChip v1.1
 
Contributor(s) Kellermayer R, Harris RA
Citation(s) 24937444
Submission date Sep 15, 2011
Last update date Mar 28, 2022
Contact name R. Alan Harris
E-mail(s) rharris1@bcm.edu
Organization name Baylor College of Medicine
Department Molecular and Human Genetics
Street address 1 Baylor Plaza
City Houston
State/province TX
ZIP/Postal code 77030
Country USA
 
Platforms (1)
GPL13534 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)
Samples (25)
GSM796576 normal colon mucosa Kelle10
GSM796577 normal colon mucosa Kelle13
GSM796578 normal colon mucosa Kelle14
This SubSeries is part of SuperSeries:
GSE32149 DNA methylation in Crohns' disease and ulcerative colitis
Relations
BioProject PRJNA154955

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE32146_RAW.tar 183.1 Mb (http)(custom) TAR
GSE32146_matrix_processed_colonMucosa.txt.gz 38.4 Mb (ftp)(http) TXT
GSE32146_matrix_signal_colonMucosa.txt.gz 65.2 Mb (ftp)(http) TXT
Processed data included within Sample table
Processed data are available on Series record
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