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Status |
Public on Aug 10, 2011 |
Title |
Gene expression arrays for different dendritic cell subset |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
|
Summary |
To further distinguish the different subset of DCs, changes in gene expression were analyzed using Agilent mouse gene expression 4×44,000 microarrays. BALB/C mouse bone marrow–derived imDCs and maDCs were generated from bone marrow progenitors. Bone marrow hematopoietic progenitor cells cocultured with Sca-1+Lin-CD117- MSCs could differentiate into a novel IL-10-dependent regDC subset-sDCs. The gene expression differentiations of the four groups (imDCs, maDCs, sDCs and neutralizing antibody-IL-10-treated sDCs) were analyzed by GeneChip microarray.
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Overall design |
The formed four groups of cells (imDCs, maDCs, sDCs and neutralizing antibody-IL-10-treated sDCs) were purified respectively, and then gene expression in them was measured.
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Contributor(s) |
Liu X |
Citation(s) |
22753940 |
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Submission date |
Aug 09, 2011 |
Last update date |
Jan 12, 2017 |
Contact name |
Xuebin Qu |
Organization name |
Institute of Basic Medical Sciences & School of Basic Medicine
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Street address |
5 Dongdansantiao
|
City |
Beijing |
ZIP/Postal code |
100005 |
Country |
China |
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Platforms (1) |
GPL7202 |
Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Probe Name version) |
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Samples (4)
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GSM775008 |
neutralizing antibody-IL-10-treated sDCs |
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Relations |
BioProject |
PRJNA146139 |