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Series GSE30566 Query DataSets for GSE30566
Status Public on Aug 03, 2011
Title Transcriptome Analysis of Human Diabetic Kidney Disease (Control Glomeruli vs. Control Tubuli)
Organism Homo sapiens
Experiment type Expression profiling by array
Summary We identified 1,700 differentially expressed probesets in DKD glomeruli and 1,831 in diabetic tubuli; 330 probesets were commonly differentially expressed in both compartments. The canonical complement signaling pathway was determined to be statistically differentially regulated in both DKD glomeruli and tubuli and was associated with increased glomerulosclerosis even in an additional set of DKD samples.
Overall design Affymetrix expression arrays were used to identify differentially regulated transcripts in 44 microdissected human kidney samples. Stringent statistical analysis using the Benjamini_Hochberg corrected 2-tailed t-test was used to identify differentially expressed transcripts in control and diseased glomeruli and tubuli.
This Series includes control glomeruli and tubuli samples.
Contributor(s) Park AS, Mohtat D, Thomas DB, Woroniecka K, Susztak K
Citation(s) 21752957
Submission date Jul 11, 2011
Last update date Dec 06, 2018
Contact name Karolina Woroniecka
Organization name AECOM
Lab Susztak
Street address 1300 Morris Park Ave
City Bronx
State/province NY
ZIP/Postal code 10461
Country USA
Platforms (1)
GPL571 [HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Samples (25)
GSM758485 Control Human Glomeruli 33
GSM758486 Control Human Glomeruli 34
GSM758487 Control Human Glomeruli 76
This SubSeries is part of SuperSeries:
GSE30122 Transcriptome Analysis of Human Diabetic Kidney Disease
BioProject PRJNA154765

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE30566_RAW.tar 52.1 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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