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Series GSE29689 Query DataSets for GSE29689
Status Public on Jun 03, 2011
Title SW480 Signaling Hub Inhibition
Organism Homo sapiens
Experiment type Expression profiling by array
Summary In tumor cells, stepwise oncogenic deregulation of signaling cascades induces alterations of cellular morphology and promotes the acquisition of malignant traits. Using a panel of small molecular inhibitors, we established associated gene expression signatures of key signaling hubs.
 
Overall design SW480 cells were grown in DMEM, 10% FCS, and treated for 24h with the following inhibitors or with solvent (DMSO): SU5402 (42uM); U0126 (10uM), SP600125 (20uM), LY294002 (20uM)
 
Contributor(s) Morkel M, Leushacke M
Citation(s) 21853123
Submission date Jun 02, 2011
Last update date Mar 20, 2017
Contact name Markus Morkel
E-mail(s) morkel@molgen.mpg.de
Phone +493084131332
Organization name Max Planck Institute for Molecular Genetics
Department Developmental Genetics
Lab Tumor Progression
Street address Ihnestr. 73
City Berlin
State/province Berlin
ZIP/Postal code 13187
Country Germany
 
Platforms (1)
GPL6883 Illumina HumanRef-8 v3.0 expression beadchip
Samples (15)
GSM736459 SW480-LY294002-1
GSM736460 SW480-DMSO-1
GSM736461 SW480-SU5402-1
Relations
BioProject PRJNA141107

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE29689_RAW.tar 3.9 Mb (http)(custom) TAR
GSE29689_non-normalized_data.txt.gz 3.4 Mb (ftp)(http) TXT
Processed data included within Sample table

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