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Series GSE2959 Query DataSets for GSE2959
Status Public on Jul 21, 2005
Title Genome-wide SNP Microarray Mapping in Basal Cell Carcinomas Unveils Uniparental Disomy as a Key Somatic Event.
Organism Homo sapiens
Experiment type Genome variation profiling by SNP array
SNP genotyping by SNP array
Summary Affymetrix 10K SNP mapping arrays were used to profile 14 basal cell carcinomas (BCCs) with matched blood DNA samples. Loss of heterozygosity (LOH) and copy number abnormality (CNA) profiles were derived from each tumour-blood pair.
Keywords: Genomic DNA on Affymetrix 10K SNP array
Overall design 14 BCC/Blood pairs were used in this study to obtain genome-wide SNP profiles. By comparing tumour and blood DNA, LOH for each SNP could be obtained. Signal intensity for each SNP were used to deternime CNA.
Contributor(s) Teh MT, Blaydon D, Chaplin T, Foot NJ, Skoulakis S, Raghavan M, Harwood CA, Proby CM, Philpott MP, Young BD, Kelsell DP
Citation(s) 16204023
Submission date Jul 18, 2005
Last update date Mar 16, 2012
Contact name Muy-Teck Teh
Phone +442078827140
Organization name Queen Mary University of London
Department Centre for Clinical & Diagnostic Oral Sciences
Lab Head & Neck Cancer Unit
Street address Blizard Building, 4, Newark Street,
City London
State/province England
ZIP/Postal code E1 2AT
Country United Kingdom
Platforms (2)
GPL1266 [Mapping10K_Xba131] Affymetrix Human Mapping 10K SNP Array
GPL2641 [Mapping10K_Xba142] Affymetrix Human Mapping 10K 2.0 Array
Samples (28)
GSM64198 Patient#1 Blood DNA
GSM64199 Patient#1 BCC DNA
GSM64200 Patient #2 Blood DNA
BioProject PRJNA92633

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Supplementary file Size Download File type/resource
GSE2959_RAW.tar 25.4 Mb (http)(custom) TAR (of TXT)

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