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Status |
Public on May 13, 2011 |
Title |
Cocaine-regulated expression of striatal microRNAs |
Organism |
Mus musculus |
Experiment type |
Non-coding RNA profiling by high throughput sequencing
|
Summary |
We cataloged miRNA expression in the nucleus accumbens and at striatal synapses in control and chronically cocaine-treated mice. We identified cocaine-responsive miRNAs, synaptically-enriched and depleted miRNA families, and confirmed cocaine-induced changes in protein expression for several predicted synaptic target genes.
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Overall design |
Analysis of small RNA from Mus musculus nucleus accumbens (NAc) and postsynaptic densities (PSD) with and without chronic cocaine treatment.
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Contributor(s) |
Eipper-Mains JE, Kiraly DD, Palakodeti D, Mains RE, Eipper BA, Graveley BR |
Citation(s) |
21708909 |
Submission date |
May 12, 2011 |
Last update date |
May 15, 2019 |
Contact name |
Brenton R Graveley |
E-mail(s) |
graveley@uchc.edu
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Phone |
860-679-2090
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Organization name |
University of Connecticut Health Center
|
Department |
Genetics and Genome Sciences
|
Street address |
400 Farmington Avenue
|
City |
Farmington |
State/province |
CT |
ZIP/Postal code |
06030-3301 |
Country |
USA |
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Platforms (1) |
GPL11002 |
Illumina Genome Analyzer IIx (Mus musculus) |
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Samples (4)
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Relations |
SRA |
SRP006784 |
BioProject |
PRJNA140265 |