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Series GSE28835 Query DataSets for GSE28835
Status Public on Jun 01, 2011
Title Large airway epithelial cells from cigarette smokers with and without lung cancer undergoing flexible bronchoscopy in the operating room for resection of a suspicious lung nodule
Organism Homo sapiens
Experiment type Expression profiling by array
Summary mRNA expression was assayed from bronchial epithelial cell samples from smokers with and without lung cancer. A subset of the samples (2 of the lung cancer samples and 3 of the no cancer samples) were pooled and underwent whole transcriptome sequencing. The goals were to compare whole transcriptome sequencing gene expression levels to gene expression levels derived from these samples run on the Affymetrix HGU133A 2.0 platform.
 
Overall design Current and former smokers with cancer (n=8) and without cancer (n=5) undergoing flexible bronchoscopy in the operating room for resection of a suspicious lung nodule at Boston University Medical Center were recruited. Patients were classified as having no lung cancer based on the pathological results from the lung biopsy. Patients with no cancer were diagnosed with alternative benign diseases of the chest including organizing pneumonitis, sarcoidosis and chronic inflammation due to foreign body material.
 
Contributor(s) Beane J
Citation(s) 21636547
Submission date Apr 25, 2011
Last update date Mar 23, 2012
Contact name Avrum Spira
E-mail(s) aspira@lung.bumc.bu.edu
Phone 617-638-4860
Fax 617-536-8093
URL http://www.pulmonomics.org
Organization name Boston University Medical Center
Department Pulmonary and Critical Care Medicine
Lab Pulmonomics Lab
Street address 715 Albany Street, R304
City Boston
State/province MA
ZIP/Postal code 02118
Country USA
 
Platforms (1)
GPL13447 Affymetrix GeneChip Human Genome U133A 2.0 Array [CDF: Ensembl v58, Hs133Av2_Hs_ENSG]
Samples (13)
GSM714147 BT13
GSM714148 BT16
GSM714149 BT18
This SubSeries is part of SuperSeries:
GSE29007 Human Large Airway Epithelial Cells from healthy never and current smoker and smokers with and without lung cancer
Relations
BioProject PRJNA153967

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE28835_RAW.tar 33.1 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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