GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE28453 Query DataSets for GSE28453
Status Public on Oct 17, 2013
Title Dynamics of Sox2 and Esrrb occupancy during the differentiation of embryonic stem cells into trophoblast stem cells.
Organism Mus musculus
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary To understand the mechanism underlying the versatility in transcriptional regulation by Sox2 and Esrrb, we compared genome-wide binding sites of Sox2 and Esrrb in embryonic stem (ES) cells and trophoblast stem (TS) cells by chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq).
Overall design A tetracycline-inducible Oct3/4 knockout ES cell line ZHBTc4 was treated with Tet for 4 days in the presence of FGF4 and mouse embryonic fibroblasts (MEFs).
Contributor(s) Adachi K, Nikaido I, Ura H, Ueda HR, Niwa H
Citation(s) 24120664
Submission date Apr 07, 2011
Last update date May 15, 2019
Contact name Itoshi NIKAIDO
Organization name RIKEN
Department Center for Biosystems Dynamics Research
Lab Laboratory for Bioinformatics Research
Street address 2-1 Hirosawa
City Wako
State/province Saitama
ZIP/Postal code 351-0198
Country Japan
Platforms (1)
GPL11002 Illumina Genome Analyzer IIx (Mus musculus)
Samples (11)
GSM703186 Sox2 ChIP-seq, Oct3/4KO Day0
GSM703187 Sox2 ChIP-seq, Oct3/4KO Day1
GSM703188 Sox2 ChIP-seq, Oct3/4KO Day2
This SubSeries is part of SuperSeries:
GSE28455 Sox2-regulatory networks in embryonic and trophoblast stem cells
SRA SRP006420
BioProject PRJNA143235

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE28453_RAW.tar 737.1 Mb (http)(custom) TAR (of BW)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap