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Series GSE28205 Query DataSets for GSE28205
Status Public on Feb 28, 2013
Title Transcriptional profiles of MET transformed osteoblast clones (MET-HOB) and mesenchymal stem cells (MSC) where osteoblast differentiation was induced
Organism Homo sapiens
Experiment type Expression profiling by array
Summary The osteogenic differentiation process consists in a well-coordinated multi-step sequence of events, in which each stage is characterized by the expression of distinct protein markers, as well as by individual morphological features. In order to precisely identify the step at which cells are permissive to MET-driven transformation, we used expression profiling. We compared the transcriptional profiles of MET-HOB and MSC cells where osteoblast differentiation was induced.
 
Overall design Using microarrays, we evaluated the expression profiles of MET-HOB and MSC cells where osteoblast differentiation was induced, by culturing cells in the presence of ascorbic acid, α-glycerophosphate and dexamethasone for 7, 14 and 21 days
 
Contributor(s) Dani N, Olivero M, Mareschi K, vanDuist M, Miretti S, Cuvertino S, Patané S, Calogero RA, Ferracini R, Scotlandi K, Fagioli F, DiRenzo M
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Submission date Mar 28, 2011
Last update date Mar 20, 2017
Contact name Raffaele A Calogero
E-mail(s) raffaele.calogero@unito.it
Phone ++39 0116706454
Organization name University of Torino
Department Molecular Biotechnology Center
Lab Bioinformatics and Genomics Unit
Street address Via Nizza 52
City Torino
State/province To
ZIP/Postal code 10126
Country Italy
 
Platforms (1)
GPL6883 Illumina HumanRef-8 v3.0 expression beadchip
Samples (16)
GSM698424 MET transformed HOB clones [C12]
GSM698425 MET transformed HOB clones [C15]
GSM698426 MET transformed HOB clones [C42]
Relations
BioProject PRJNA139645

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE28205_RAW.tar 3.9 Mb (http)(custom) TAR
GSE28205_non_normalized.txt.gz 2.5 Mb (ftp)(http) TXT
GSE28205_normalized.txt.gz 2.4 Mb (ftp)(http) TXT
Processed data included within Sample table
Processed data are available on Series record

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