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Series GSE2815 Query DataSets for GSE2815
Status Public on Jun 14, 2005
Title cMyb and vMyb in MCF7 cells
Organism Homo sapiens
Experiment type Expression profiling by array
Summary The transcriptional activities of c-Myb and its oncogenic variant v-Myb were compared by expressing them in human MCF7 cells using recombinant adenovirus vectors. A hybrid construct, 3Mutc, which is a variant of c-Myb harboring three v-Myb-derived DNA binding domain mutations was also analyzed. All the samples were compared to cells infected with a control adenovirus. The results showed that v-Myb, which differs from c-Myb only by N- and C-terminal deletions and eleven amino acid substitutions, has a qualitatively different transcriptional activity.
Keywords: repeat
Overall design 2 replicates of each type were analyzed. Replicates were performed independently, more than a week apart.
Contributor(s) Liu F, Lei W, O'Rourke JP, Ness SA
Citation(s) 16205643
Submission date Jun 14, 2005
Last update date Aug 10, 2018
Contact name Scott A. Ness
Phone 505-272-9883
Organization name U. of New Mexico HSC
Department Internal Medicine
Lab Ness
Street address MSC07 4025 - CRF 121
City Albuquerque
State/province NM
ZIP/Postal code 87131-0001
Country USA
Platforms (1)
GPL96 [HG-U133A] Affymetrix Human Genome U133A Array
Samples (8)
GSM60915 control virus-infected replicate 1 (MCF7)
GSM60916 control virus-infected replicate 2 (MCF7)
GSM60917 cMyb virus-infected replicate 1 (MCF7)
BioProject PRJNA92417

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SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE2815_RAW.tar 24.7 Mb (http)(custom) TAR (of CEL)

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