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| Status |
Public on Sep 17, 2013 |
| Title |
Gene expression analysis in a variety of normal, premalignant and squamous cell carcinomas of the cervix |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
We sought to apply the technologies of gene expression profiling to detect genes significant in the aetiology of cervical carcinoma . We investigated 14 normal (NAD), 11 low grade squamous intrapepithelial lesions (LSIL), 21 high grade squamous intraepithelial lesions (HSIL) and 28 squamous cell carcinomas by Affymetrix GeneChip whole transcriptome profiling. Two SCC cell lines were also included in the cohort. Normal and SILS were profiled using the Affymetrix U133A platform, while SCCs and Cell lines were profiled using the Affymetrix U133A plus 2.0 array.
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| Overall design |
This submission describes the transcriptional profiles of a cohort totalling 77 cervical normal, premalignant lesions, and squamous cell carcinomas
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| Contributor(s) |
Karagavriilidou K, Roberts I, Carter S, Ng G, Gooding E, Chattopadhyay A, Pett M, Murray M, Winder D, Muralidhar B, Ward D, Stacey P, Philips M, Scarpini C, Mukherjee G, Coleman N |
| Citation(s) |
17516585, 21952923, 23765377 |
| |
| Submission date |
Mar 04, 2011 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Ian Roberts |
| E-mail(s) |
ian.roberts@cantab.net
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| Phone |
0044 1223 763 279
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| Organization name |
Hutchison MRC Research Centre
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| Department |
Cancer Cell Unit
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| Lab |
Coleman
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| Street address |
Hills Road
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| City |
Cambridge |
| ZIP/Postal code |
CB2 0XZ |
| Country |
United Kingdom |
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| Platforms (2) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
| GPL571 |
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array |
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| Samples (77)
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| This SubSeries is part of SuperSeries: |
| GSE27333 |
Gain of the oncostatin M receptor in cervical squamous cell carcinoma is associated with adverse clinical outcome |
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| Relations |
| BioProject |
PRJNA138175 |
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