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Series GSE27678 Query DataSets for GSE27678
Status Public on Sep 17, 2013
Title Gene expression analysis in a variety of normal, premalignant and squamous cell carcinomas of the cervix
Organism Homo sapiens
Experiment type Expression profiling by array
Summary We sought to apply the technologies of gene expression profiling to detect genes significant in the aetiology of cervical carcinoma . We investigated 14 normal (NAD), 11 low grade squamous intrapepithelial lesions (LSIL), 21 high grade squamous intraepithelial lesions (HSIL) and 28 squamous cell carcinomas by Affymetrix GeneChip whole transcriptome profiling. Two SCC cell lines were also included in the cohort. Normal and SILS were profiled using the Affymetrix U133A platform, while SCCs and Cell lines were profiled using the Affymetrix U133A plus 2.0 array.
Overall design This submission describes the transcriptional profiles of a cohort totalling 77 cervical normal, premalignant lesions, and squamous cell carcinomas
Contributor(s) Karagavriilidou K, Roberts I, Carter S, Ng G, Gooding E, Chattopadhyay A, Pett M, Murray M, Winder D, Muralidhar B, Ward D, Stacey P, Philips M, Scarpini C, Mukherjee G, Coleman N
Citation(s) 17516585, 21952923, 23765377
Submission date Mar 04, 2011
Last update date Mar 25, 2019
Contact name Ian Roberts
Phone 0044 1223 763 279
Organization name Hutchison MRC Research Centre
Department Cancer Cell Unit
Lab Coleman
Street address Hills Road
City Cambridge
ZIP/Postal code CB2 0XZ
Country United Kingdom
Platforms (2)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
GPL571 [HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Samples (77)
GSM685524 normal_N21_expression
GSM685525 SCC_K3_expression
GSM685526 SCC_N98_expression
This SubSeries is part of SuperSeries:
GSE27333 Gain of the oncostatin M receptor in cervical squamous cell carcinoma is associated with adverse clinical outcome
BioProject PRJNA138175

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE27678_RAW.tar 236.1 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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