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Series GSE27135 Query DataSets for GSE27135
Status Public on Feb 15, 2013
Title Affymetrix SNP array data for different passages of mesenchymal stem cells.
Organism Homo sapiens
Experiment type Genome variation profiling by SNP array
Summary Cells in culture undergo replicative senescence and unequivocally stop proliferation after a limited number of cell divisions. In this study, we have expanded mesenchymal stem cells (MSC) from human adipose tissue and analyzed genetic and epigenetic sequels. The subpopulation of highly proliferative cells and the in vitro differentiation potential decayed already within early passages. Relevant chromosomal aberrations were not detected by karyotyping and SNP-microarrays.
 
Overall design Comparison of early and late passage of five samples of mesenchymal stem cells from human adipose tissue.
 
Contributor(s) Schellenberg A, Lin Q, Schüler H, Koch CM, Joussen S, Denecke B, Bokermann G, Pallua N, Suschek CV, Zenke M, Wagner W
Citation(s) 22025769
Submission date Feb 08, 2011
Last update date Nov 27, 2018
Contact name Lin Gan
Organization name University Hospital Aachen
Department IZKF
Lab Genomics facility
Street address Pauwelsstr. 30
City Aachen
ZIP/Postal code 52074
Country Germany
 
Platforms (1)
GPL6801 [GenomeWideSNP_6] Affymetrix Genome-Wide Human SNP 6.0 Array
Samples (10)
GSM670520 donor 4 (AT25)_passage 5
GSM670521 donor 4 (AT25)_passage 10
GSM670522 donor 8 (AT27)_passage 5
Relations
BioProject PRJNA137655

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE27135_RAW.tar 620.1 Mb (http)(custom) TAR (of CEL, CNCHP)
Processed data included within Sample table
Processed data provided as supplementary file

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