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Series GSE26888 Query DataSets for GSE26888
Status Public on Apr 01, 2011
Title Expression data from HeLa cells transiently transfected with control siRNA or SON siRNA
Organism Homo sapiens
Experiment type Expression profiling by array
Summary SON is a large Ser/Arg (SR)-related protein localized in nuclear speckles. SON siRNA causes defects in mitotic progression and genome instability. We used microarrays to detail the pattern of gene expression after SON knockdown.
Overall design HeLa cells were grown in 100 mm dishes and transfected with negative control siRNA or SON siRNA (400 pmol). Then, cells were harvested after 66 hours and RNAs were isolated. Microarrays were performed using GeneChip Human Genome U133A 2.0 (Affymetrix).
Contributor(s) Ahn E, DeKelver RC, Lo M, Nguyen TA, Matsuura S, Boyapati A, Pandit S, Fu X, Zhang D
Citation(s) 21504830
Submission date Jan 26, 2011
Last update date Dec 06, 2018
Contact name Dong-Er Zhang
Phone 858-822-5372
Organization name University of California San Diego
Department Cancer Center
Lab Zhang
Street address 3855 Health Sciences Drive, Mail Stop 0815
City La Jolla
State/province CA
ZIP/Postal code 92093
Country USA
Platforms (1)
GPL571 [HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Samples (6)
GSM662184 control siRNA rep1
GSM662185 SON siRNA rep1
GSM662186 control siRNA rep2
BioProject PRJNA135949

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Supplementary file Size Download File type/resource
GSE26888_RAW.tar 19.5 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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