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| Status |
Public on Feb 28, 2012 |
| Title |
Genome-wide analysis of cellular SMD or NMD substrates that regulated by Upf1 or PNRC2 in HeLa cell |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Analysis of cellular SMD or NMD substrates that regulated by Upf1 and/or PNRC2 in HeLa cell. The hypothesis tested in the present study was that endogenous SMD or NMD substrates may co-regulated by Upf1 and PNRC2. Results provide important information that vast range of cellular SMD or NMD substrates are reqired PNRC2 for decay.
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| Overall design |
Total RNA obtained from HeLa cells with downregulation of Upf1 or PNRC2 by siRNA. The up- or down-regulated transcripts were compare to control siRNA treated HeLa cell RNA extract. Significant transcripts were confirmed by replication
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| |
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| Contributor(s) |
Cho H, Kim K, Choe J |
| Citation(s) |
22503102 |
| Submission date |
Jan 21, 2011 |
| Last update date |
Mar 20, 2017 |
| Contact name |
Hana Cho |
| E-mail(s) |
sweet-akasia@hanmail.net
|
| Phone |
82-2-3290-3919
|
| Organization name |
Korea University
|
| Department |
School of Life Sciences and Biotechnology
|
| Lab |
Molecular Genomics
|
| Street address |
Anam 5ga, Sungbukku
|
| City |
Seoul |
| ZIP/Postal code |
136-701 |
| Country |
South Korea |
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| Platforms (1) |
| GPL6883 |
Illumina HumanRef-8 v3.0 expression beadchip |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA136279 |
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