|
| Status |
Public on Jul 31, 2024 |
| Title |
Pharmacological Repositioning of the transcription factor PU.1 [PRO-seq] |
| Organism |
Homo sapiens |
| Experiment type |
Other
|
| Summary |
This study aims to investigate the effects of PU.1 binding-site inhibitors/redistributors (DB2115) upon nascent transcription in AML cell lines
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| |
|
| Overall design |
The MOLM-13 cell line were treated with 5uM of DB compound for 0,1, 4 & 12hr, before cells were harvested for Precision nuclear run on and sequencing (PRO-seq).
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| |
|
| Contributor(s) |
Steidl U, Taylor S |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
May 14, 2024 |
| Last update date |
Jul 31, 2024 |
| Contact name |
Samuel John Taylor |
| E-mail(s) |
samueljtaylor89@gmail.com
|
| Organization name |
Albert Einstein College of Medicine
|
| Street address |
1300 Morris Park Ave, Chanin building 601
|
| City |
Bronx |
| State/province |
NY |
| ZIP/Postal code |
10461 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (8)
|
| GSM8264959 |
MOLM13, 5uM DB2115, 1hr PRO-seq rep2 |
| GSM8264960 |
MOLM13, 5uM DB2115, 4hr PRO-seq rep1 |
| GSM8264961 |
MOLM13, 5uM DB2115, 4hr PRO-seq rep2 |
| GSM8264962 |
MOLM13, 5uM DB2115, 12hr PRO-seq rep1 |
| GSM8264963 |
MOLM13, 5uM DB2115, 12hr PRO-seq rep2 |
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| This SubSeries is part of SuperSeries: |
| GSE267389 |
Pharmacological Repositioning of the transcription factor PU.1 |
|
| Relations |
| BioProject |
PRJNA1111389 |
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