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Series GSE26489 Query DataSets for GSE26489
Status Public on Jan 15, 2011
Title Gene expression under normoxia and hypoxia in mouse embryonic fibroblasts
Organism Mus musculus
Experiment type Expression profiling by array
Summary Mouse and human somatic cells can be reprogrammed to induced pluripotent stem cells (iPSCs) by the transduction of four transcription factors, Oct 3/4, Sox2, Klf4, and c-Myc. Conducting reprogramming in hypoxic conditions was shown to result in improved efficiency for both mouse and human cells. To examine the effect of hypoxic cultivation, we performed microarray analyses using mouse embryonic fibroblasts cultivated under normoxia and hypoxia.
Overall design Mouse embryonic fibroblasts and four factor-transduced reprogramming fibroblasts were grown under normoxia and hypoxia. These cells were used for microarray analyses.
Contributor(s) Yoshida Y, Takahashi K, Okita K, Ichisaka T, Yamanaka S
Citation(s) 19716359
Submission date Jan 07, 2011
Last update date Jan 12, 2017
Contact name Shinya Yamanaka
Phone 81-75-366-7041
Organization name Center for iPS Cell Research and Applicaton (CiRA), Kyoto University
Street address 53 Kawahara-machi, Shogoin, Sakyo-ku
City Kyoto
ZIP/Postal code 606-8507
Country Japan
Platforms (1)
GPL7202 Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Probe Name version)
Samples (4)
GSM651347 MEF 4F under 21% O2
GSM651348 MEF 4F under 5% O2
GSM651349 MEF under 21% O2
BioProject PRJNA136489

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE26489_RAW.tar 31.5 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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