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| Status |
Public on Sep 18, 2024 |
| Title |
Transcriptomic analysis of rhabdomyolysis induced kidney injury |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Acute kidney injury (AKI) represents a syndrome seldom characterized by a single, distinct pathophysiological cause. Rhabdomyolysis-induced acute kidney injury (RIAKI) constitutes roughly 15% of AKI cases, yet its underlying pathophysiology remains poorly understood. Using a murine model of RIAKI induced by muscular glycerol injection, we aimed to analyse transcriptomic alterations by RNAseq.
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| Overall design |
We analysed kidneys lysates following 24 hours of AKI induction by rhabdomyolysis (N=6) to obtain a transcriptomic profile at a stage of beginning kidney failure (significant raise of creatinine).
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| Contributor(s) |
Kulow VA, Labes R, Fähling M |
| Citation(s) |
39042141 |
| |
| Submission date |
Apr 23, 2024 |
| Last update date |
Sep 19, 2024 |
| Contact name |
Robert Labes |
| E-mail(s) |
robert.labes@charite.de
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| Organization name |
Charité - Universitätsmedizin Berlin
|
| Department |
Institute of Translational Physiology
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| Street address |
Charitéplatz 1
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| City |
Berlin |
| ZIP/Postal code |
10117 |
| Country |
Germany |
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| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA1103748 |
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