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Series GSE262931 Query DataSets for GSE262931
Status Public on Jul 05, 2024
Title Variants in tubule epithelial regulatory elements mediate most heritable differences in human kidney function
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary We used bulk and single-cell ATAC-seq to measure chromatin accessibilty in human kidneys. This allowed us to define candidate cis-regulatory elements of each human kidney cell type and identify the role of podocyte and tubule regulatory elements in human kidney function.
 
Overall design Single cell ATAC-sequencing of 3 human kidneys. Single cell ATAC-sequencing was performed on cortex from all 3 kidneys and medulla from two of the kidneys.
Bulk ATAC-sequencing from the cortex of one human kidney was also performed.

**Please note that the records have been updated with additional data on Aug 8, 2024.****
 
Contributor(s) Loeb GB, Reiter JF
Citation(s) 39256582
Submission date Apr 01, 2024
Last update date Sep 26, 2024
Contact name Gabriel Loeb
E-mail(s) gabriel.loeb@ucsf.edu
Organization name UCSF
Department Medicine
Street address 555 Mission Bay Blvd South, Rm 382H
City San Francisco
State/province CA
ZIP/Postal code 94143
Country USA
 
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (6)
GSM8181664 Donor 1 cortex
GSM8181665 Donor 2 cortex
GSM8181666 Donor 2 medulla
Relations
BioProject PRJNA1094933

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE262931_ArchR_project.zip 11.7 Gb (ftp)(http) ZIP
GSE262931_CellTypeSpecificPeakClusters.tar.gz 4.1 Mb (ftp)(http) TAR
GSE262931_RAW.tar 17.0 Gb (http)(custom) TAR (of BW, H5, NARROWPEAK, TBI, TSV)
GSE262931_scATAC_Bigwigs.tar.gz 6.2 Gb (ftp)(http) TAR
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Raw data are available in SRA

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