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| Status |
Public on Mar 04, 2024 |
| Title |
O-GlcNAcylation of CTCF regulates 3D chromatin structure [HiC] |
| Organism |
Mus musculus |
| Experiment type |
Other
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| Summary |
The goal of this study is to test whether the O-GlcNAcylation of CTCF plays a role in regulating chromatin structure.
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| Overall design |
We used HiC to test the changes of 3D chromtin sttucture after muating the O-GlcNAcylation of CTCF. ChIP-seq was used to test the function of O-GlcNAcylation in CTCF chromatin binding. RNA-seq was perforemed to test the changes of genes expression in same condition. ATAC-seq was used to test the change of the chromatin accessibility.
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| Contributor(s) |
Ding J, Tang X, Zeng P |
| Citation(s) |
38561336 |
| BioProject |
PRJNA1070848 |
| |
| Submission date |
Feb 15, 2024 |
| Last update date |
Apr 17, 2024 |
| Contact name |
Zeng Pengguihang |
| E-mail(s) |
zengpgh@mail3.sysu.edu.cn
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| Organization name |
Sun Yat-Sen University
|
| Street address |
No.74, Zhongshan 2nd Road, Guangzhou, Guangdong
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| City |
Guanghzou |
| ZIP/Postal code |
510080 |
| Country |
China |
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| Platforms (1) |
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| Samples (6)
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| This SubSeries is part of SuperSeries: |
| GSE255897 |
O-GlcNAcylation of CTCF regulates 3D chromatin structure |
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