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Series GSE252175 Query DataSets for GSE252175
Status Public on May 17, 2024
Title Multi-Omics molecular subtyping based on commensal microbiome predicts molecular characteristics and therapeutic response in Triple-Negative Breast Cancer [scRNA-seq]
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary We thoroughly analyzed the molecular subtyping of Triple-Negative Breast Cancer and its different manifestations, and located T cells and Tumor cells related to the survival of breast cancer through single cell sequencing and space transcriptome according to our score, and finally investigated their relationship with the therapeutic efficacy, providing a scientific basis for the treatment of triple negative breast cancer.
 
Overall design 10x Single-cell Transcriptome sequencing were used to obtain the characteristics of 2 TNBC samples, and 10x Spatial Transcriptome sequencing were used to obtain the characteristics of 4 TNBC samples.
 
Contributor(s) Qi F, Li J, Gao N, Qin W
Citation(s) 38730464
Submission date Dec 28, 2023
Last update date May 18, 2024
Contact name Qi Feng
E-mail(s) qf12486@rjh.com.cn
Organization name Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Department Department of Oncology
Street address No. 197 Ruijin Second Road
City Shanghai
ZIP/Postal code 200000
Country China
 
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (2)
GSM7996199 TNBC tissue, replicate 1
GSM7996200 TNBC tissue, replicate 2
Relations
BioProject PRJNA1058410

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE252175_RAW.tar 165.3 Mb (http)(custom) TAR (of MTX, TSV)
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Raw data are available in SRA

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