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| Status |
Public on Feb 16, 2024 |
| Title |
Spatial transcriptome analysis unveils an innate immune activation signature of acute T cell-mediated rejection in kidney transplants |
| Organism |
Homo sapiens |
| Experiment type |
Other
|
| Summary |
To unveil the molecular mechanisms underlying TCMR, we utilized spatial transcriptomics on post-transplant TCMR and non-TCMR patients. Contrary to the prevailing T cell-centric view, our findings reveal uniform inflammatory responses across glomerular and tubulointerstitial regions in TCMR.
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| |
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| Overall design |
Kidney biopsy samples
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| |
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| Contributor(s) |
Kang M, Kwon H, Kim Yc, Kim HJ |
| Citation missing |
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| |
| Submission date |
Dec 27, 2023 |
| Last update date |
Feb 16, 2024 |
| Contact name |
Minji Kang |
| E-mail(s) |
minzi@snu.ac.kr
|
| Organization name |
Seoul National University graduate school
|
| Department |
biomedical sciences
|
| Street address |
103 daehak-ro
|
| City |
Seoul |
| ZIP/Postal code |
03080 |
| Country |
South Korea |
| |
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| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA1057859 |
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