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| Status |
Public on Jan 01, 2024 |
| Title |
CDAHFD induced NASH mouse model |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Non-alcoholic steatohepatitis (NASH) is the most significant cause of chronic liver disease worldwide, with limited therapeutic options. In this experiment, a choline-deficient amino acid-defined high fat diet (CDAHFD) were used to construct a mouse NASH model. After 16 weeks of CDAHFD diets, liver samples were collected. We want to further confirm that the elevated EFHD2 is specifically expressed in infiltrated macrophages/monocytes in NASH.
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| Overall design |
Animal experiments were conducted using CDAHFD induced NASH models in C57BL/6J mice.Prepare mouse liver as a single-cell suspension.
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| Contributor(s) |
Fu J, Wang P, Liu Y |
| Citation missing |
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| Submission date |
Sep 13, 2023 |
| Last update date |
Jan 01, 2024 |
| Contact name |
Jiangtao Fu |
| E-mail(s) |
yczxfjt@hotmail.com
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| Organization name |
Naval medical university
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| Street address |
Guohe Road 325
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| City |
Shanghai |
| ZIP/Postal code |
200433 |
| Country |
China |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (1) |
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| Relations |
| BioProject |
PRJNA1016334 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE243079_RAW.tar |
81.5 Mb |
(http)(custom) |
TAR (of MTX, TSV) |
SRA Run Selector |
| Raw data are available in SRA |
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