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Series GSE241738 Query DataSets for GSE241738
Status Public on Mar 04, 2024
Title Enhancer-activated RET confers protection against oxidative stress to the MLL-rearranged acute myeloid leukemia cells
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary RET expression is upregulated in AML subtypes harboring genetic fusions of MLL-1 genes compared to age-matched healthy donors and other AML subtypes. In addition, we identify a novel epigenetic mechanism of RET overexpression in MLL-rearranged AML.
 
Overall design examination of chromatin accessibility in CD34 and MOLM13 cells
 
Contributor(s) Stephens KE, Choudhury SR
Citation(s) 38226414
Submission date Aug 25, 2023
Last update date Mar 04, 2024
Contact name Kimberly E Stephens
E-mail(s) kestephens@uams.edu
Phone 501-364-3307
Organization name University of Arkansas for Medical Sciences
Department Pediatrics
Street address 13 Children's Way
City Little Rock
State/province AR
ZIP/Postal code 72202
Country USA
 
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (6)
GSM7734661 CD34 cells replicate 1
GSM7734662 CD34 cells replicate 2
GSM7734663 CD34 cells replicate 3
Relations
BioProject PRJNA1009434

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE241738_NormalizedReads_CD34vsMOLM13.csv.gz 1.3 Mb (ftp)(http) CSV
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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