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| Status |
Public on Sep 01, 2023 |
| Title |
HSF-1 promotes longevity through ubiquilin-1 dependent mitochondrial remodelling |
| Organism |
Caenorhabditis elegans |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
In this experiment, we aimed to determine the gene expression changes associated with loss of UBQL-1 in wildtype and in worms overexpressing HSF-1 (hsf-1 OE).
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| Overall design |
C. elegans worms (N2 laboratory wild-type strain, ubql-1(tm1574), hsf-1 OE, and hsf-1 OE;ubql-1(tm1574)) were synchornised by egg-laying, grown at 20C and collected at Day1 of adulthood as young adults. Worms were collected and snap frozen before RNA was extracted using an RNeasy kit (Qiagen).
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| Contributor(s) |
Labbadia J, Erinjeri AP |
| Citation missing |
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| Submission date |
Aug 23, 2023 |
| Last update date |
Sep 01, 2023 |
| Contact name |
John Labbadia |
| E-mail(s) |
j.labbadia@ucl.ac.uk
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| Organization name |
UCL
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| Department |
GEE
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| Street address |
Darwin Building, Gower Street
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| City |
London |
| ZIP/Postal code |
WC1E 6BT |
| Country |
United Kingdom |
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| Platforms (1) |
| GPL26672 |
Illumina NovaSeq 6000 (Caenorhabditis elegans) |
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| Samples (16)
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| Relations |
| BioProject |
PRJNA1008701 |
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