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Series GSE237886 Query DataSets for GSE237886
Status Public on Jun 10, 2024
Title Regulatory mechanism of Sox9 gene expression in chondrocytes [ChIP-seq]
Organism Mus musculus
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary The transcription factor Sox9 (Sry-Related HMG-Box gene 9) is essential in chondrogenesis. The expression Sox9 is regulated by 1.5Mb long range genomic region in temporospatial manner and genome translocation or deletion which affect Sox9 expression cause campomelic dysplasia (CD), characterized by skeletal malformations. Although functional mechanism of Sox9 are well studied so far, regulatory mechanism of Sox9 expression and its related enhancer in chondrocytes are largely remains to be elucidated. The purpose of this study is to identify Sox9 enhancers in chondrocytes
 
Overall design ChIP-seq
 
Contributor(s) Kobayashi S, Hata K
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Jul 20, 2023
Last update date Jun 10, 2024
Contact name Kenji Hata
E-mail(s) hata.kenji.dent@osaka-u.ac.jp
Phone +81-6-6879-2887
Organization name Osaka University graduate school of dentistry
Department Biochemistry
Street address 1-8 Yamadaoka
City Suita
State/province Osaka
ZIP/Postal code 565-0871
Country Japan
 
Platforms (1)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
Samples (7)
GSM7655993 Cho_H3K27ac_Rep1
GSM7655994 Cho_H3K27ac_Rep2
GSM7655995 Cho_H3k4me2
This SubSeries is part of SuperSeries:
GSE237889 Regulatory mechanism of Sox9 gene expression in chondrocytes
Relations
BioProject PRJNA996990

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE237886_RAW.tar 3.3 Mb (http)(custom) TAR (of BED)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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