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| Status |
Public on Feb 07, 2024 |
| Title |
Candida albicans interaction with intestinal epithelial cells |
| Organisms |
Candida albicans; Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To characterize the interaction of Candida albicans with intestinal epithelial cells (C2BBe1) from early fungal adhesion to invasion (up to 6 h) and the late translocation and damage phase (12 -24 h), we conducted dual RNA-sequencing of C. albicans-infected C2BBe1 cells over a 24 h time course, with sampling at 0 h, 45 min, 3 h, 6 h, 12 h, and 24 h.
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| Overall design |
Gene expression profiling analysis of RNA-seq data comparing C2BBe1 cells infected with Candida albicans with C2BBe1 or C. albicans cells cultured alone, with the aim to identify infection-specific gene expression.
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| Contributor(s) |
Sprague JL, Kasper L, Allert S, Großmann P, Schäuble S, Panagiotou G, Hube B |
| Citation(s) |
38427950 |
| |
| Submission date |
Jul 17, 2023 |
| Last update date |
Mar 07, 2024 |
| Contact name |
Sascha Schäuble |
| E-mail(s) |
sascha.schaeuble@leibniz-hki.de
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| Organization name |
Leibniz Institute for Natural Product Research and Infection Biology
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| Street address |
Beutenbergstraße 11a
|
| City |
Jena |
| ZIP/Postal code |
07745 |
| Country |
Germany |
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| Platforms (2) |
| GPL18448 |
Illumina HiSeq 2000 (Candida albicans; Homo sapiens) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
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| Samples (51)
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| Relations |
| BioProject |
PRJNA995521 |
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