|
| Status |
Public on Jul 31, 2011 |
| Title |
Monocyte gene expression patterns distinguish subjects with and without atherosclerosis. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
We used microarrays to profile monocytes to identify gene expression differences correlating with disease status in carotid artery atherosclerosis. We identified 1302 genes differentially expressed between control and affected subjects after correcting for clinical covariates. Differential expression was likely caused by unidentified risk factors or systematic manifestations of atherosclerosis itself.
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| |
|
| Overall design |
Monocytes were extracted from subjects with and without carotid atherosclerosis. Microarray hybridization was used to determine if expression patterns distinguish the subjects.
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| |
|
| Contributor(s) |
Pritchard DK, Schwartz SM |
| Citation missing |
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| |
| Submission date |
Aug 23, 2010 |
| Last update date |
Mar 22, 2012 |
| Contact name |
David K Pritchard |
| E-mail(s) |
dpritch@u.washington.edu
|
| Phone |
1-206-616-8786
|
| Organization name |
University of Washington
|
| Department |
Pathology
|
| Lab |
Schwartz
|
| Street address |
815 Mercer Street Rm. 418
|
| City |
Seattle |
| State/province |
WA |
| ZIP/Postal code |
98109-4714 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL2700 |
Sentrix HumanRef-8 Expression BeadChip |
|
| Samples (95)
|
|
| Relations |
| BioProject |
PRJNA130759 |
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