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Series GSE235927 Query DataSets for GSE235927
Status Public on Sep 01, 2023
Title Preclinical Evidence for the Glucocorticoid-Sparing Potential of a Dual Toll-Like Receptor 7/8 Inhibitor in Autoimmune Diseases
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Single cell RNA-seq analysis of PBMCs testing for a synergistic effect of TLR7/8 inhibition and the glucocorticoid dexamethasone
Overall design Isolated PBMCs of four healthy human blood donor leukopaks, treated with a TLR7 and/or TLR8 inhibitor and/or dexamethasone
Web link
Contributor(s) Nicholas G, Andrew B, Evgeni T, Ankita D, Bharat V
Citation(s) 37673681
Submission date Jun 27, 2023
Last update date Dec 01, 2023
Contact name Andrew Bender
Organization name EMD Serono
Department Research Unit - Neuroscience & Immunology
Lab Discovery Biology
Street address 45 Middlesex Turnpike
City Billerica
State/province MA
ZIP/Postal code 01821
Country USA
Platforms (1)
GPL30173 NextSeq 2000 (Homo sapiens)
Samples (24)
GSM7512048 Donor 1, No Treatment
GSM7512049 Donor 1, Dex only
GSM7512050 Donor 1, R848 only
BioProject PRJNA988047

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Supplementary file Size Download File type/resource 1019.7 Mb (ftp)(http) RDS 697.5 Mb (ftp)(http) H5AD
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Processed data are available on Series record

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