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Series GSE234244 Query DataSets for GSE234244
Status Public on Feb 02, 2024
Title Amphiregulin from regulatory T cells promotes liver fibrosis and insulin resistance in non-alcoholic steatohepatitis [scTreg]
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary We study the effect of Treg cell-derived Areg in chronic liver injury. Here we look at the transcriptional changes of Treg cells in NASH compared to normal chow.
 
Overall design Single cell RNA-seq of Treg cells enriched via FACS from the liver, spleen and visceral adipose tissue from Foxp3GFP mice fed normal chow or a NASH diet.
Hashtag 1-3 are normal diet and Hashtag 4-7 are NASH.
 
Contributor(s) Arpaia N, Savage TM, Forton KT, de los Santos K, Rouanne M, Oliveras Alsina A, Cavero R, Li F, Haeusler RA, Adam J, Schwabe RF, Shayya HJ, Rae SS
Citation(s) 38309273
Submission date Jun 06, 2023
Last update date May 03, 2024
Contact name Nicholas Arpaia
E-mail(s) na2697@cumc.columbia.edu
Organization name Columbia University
Department Microbiology & Immunology
Street address 701 West 168th Street
City New York
State/province NY
ZIP/Postal code 10032
Country USA
 
Platforms (1)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (9)
GSM7458084 Treg, spleen_GEX
GSM7458085 Treg, spleen_HTO
GSM7458086 Treg, spleen_TCR
This SubSeries is part of SuperSeries:
GSE208706 Amphiregulin from regulatory T cells promotes liver fibrosis and insulin resistance in non-alcoholic steatohepatitis
Relations
BioProject PRJNA980619

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE234244_NT016.tar.gz 26.3 Mb (ftp)(http) TAR
GSE234244_NT017.tar.gz 25.3 Mb (ftp)(http) TAR
GSE234244_NT018.tar.gz 16.9 Mb (ftp)(http) TAR
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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