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Series GSE233503 Query DataSets for GSE233503
Status Public on Jun 28, 2023
Title Immunoglobulin repertoires in mice carrying a knock-in human Cµ gene downstream of the IGH 3' regulatory region
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary To in-depth analyze the repertoire of B cells after the occurrence of recombination events joining SÙ to the IgH downstream regulatory region (3'RR)
Overall design Spleen B cell RNA samples from knock-in mice, comparing the endogenous IgM µ heavy chain transcripts (VDJ spliced onto MmCµ), versus endogenous mouse spliced IgG2b gamma heavy chain transcripts (VDJ spliced to MmG2b), versus spliced VDJ-hCµ transcripts obtained after recombination close to the ectopic knock-in human Cµ gene
Contributor(s) Cogné M, ROSSILLE D
Citation(s) 37359540
Submission date May 25, 2023
Last update date Jun 29, 2023
Contact name Delphine Rossille
Organization name INSERM U1236-MOBIDIC
Street address 2 avenue du Pr. Léon Bernard
City Rennes
ZIP/Postal code 35000
Country France
Platforms (1)
GPL16417 Illumina MiSeq (Mus musculus)
Samples (33)
GSM7429694 F3R1Sept2017
GSM7429695 F3R2Sept2017
GSM7429696 F3R3Sept2017
BioProject PRJNA976398

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE233503_RAW.tar 4.1 Gb (http)(custom) TAR (of TAR)
GSE233503_stats_per_condition.xlsx 11.2 Kb (ftp)(http) XLSX
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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