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Series GSE233308 Query DataSets for GSE233308
Status Public on Dec 12, 2023
Title RNA-sequencing of mammary epithelial cell subpopulations from normal premenopausal and postmenopausal breast tissue [RNASeq_2_PrePost]
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary RNA-sequencing was performed on patient mammary epithelial cell subsets from premenopausal and postmenopausal women undergoing breast reduction surgeries to interrogate transcriptional changes in postmenopausal cells.
Overall design Lin-EPCAM+CD49F- ML, Lin- EPCAM+CD49F+ LP and Lin-EPCAM-CD49F+ basal cells were isolated from normal premenopausal (n=4 patients) and postmenopausal (n=4 patients) human breast tissue by FACS and subjected to RNA-sequencing. The postmenopausal patients included in the study were not taking hormone-replacement therapies at time of surgery.
** Submitter declares that the raw data files are not provided due to privacy concerns about the human samples***
Web link
Contributor(s) Chen Y, Joyce R, Pascual R, Smyth GK, Visvader JE
Citation(s) 38216737
Submission date May 24, 2023
Last update date Mar 12, 2024
Contact name Yunshun Chen
Organization name Walter and Eliza Hall Institute of Medical Research
Department ACRF Cancer Biology and Stem Cells
Lab Chen
Street address 1G Royal Parade
City Parkville
State/province VIC
ZIP/Postal code 3052
Country Australia
Platforms (1)
GPL30173 NextSeq 2000 (Homo sapiens)
Samples (24)
GSM7422350 Basal population from Patient 0015 [Post-Basal-0015]
GSM7422351 LP population from Patient 0015 [Post-LP-0015]
GSM7422352 ML population from Patient 0015 [Post-ML-0015]
This SubSeries is part of SuperSeries:
GSE233505 Identification of aberrant luminal progenitors and mTORC1 as a potential chemoprevention target in BRCA2 mutation carriers
BioProject PRJNA975845

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE233308_GeneCountMatrix.txt.gz 829.4 Kb (ftp)(http) TXT
GSE233308_RAW.tar 4.3 Mb (http)(custom) TAR (of TXT)
Processed data are available on Series record
Processed data provided as supplementary file
Raw data not provided for this record

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