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| Status |
Public on Sep 06, 2023 |
| Title |
Effect of Streptomyces roseolus cell free supernatant on fungal development, transcriptome and aflatoxin B1 production of Aspergillus flavus |
| Platform organism |
Penicillium expansum |
| Sample organism |
Aspergillus flavus |
| Experiment type |
Expression profiling by array
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| Summary |
Frequently observed in tropical and sub-tropical regions, crops contamination by aflatoxin B1 (AFB1) produced by Aspergillus flavus, is emerging in Europe, due to climate change. Many alternative methods are currently developed to reduce the use of chemical inputs to prevent mycotoxin contamination, such as biocontrol agents (BCAs). Actinobacteria are known to produce many bioactive compounds and some of them are able to reduce in vitro AFB1 concentration. In this context, the present study aims to analyze the effect of a cell free supernatant (CFS) from Streptomyces roseolus liquid culture on A. flavus development, as well as on its transcriptome profile using microarray assay and its impact on AFB1 concentration. To study the impact of Streptomyces roseolus cell free supernatant on global transcriptome of Aspergillus flavus we have employed whole genome microarray expression profiling.
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| Overall design |
A. flavus was exposed to Streptomyces roseolus cell free supernatant at 1.5 g/L during 5 days at 28°C. Four independent experiments were performed.
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| Contributor(s) |
Maud L, Boyer F, Mathieu F, Snini SP, Naylies C, Lippi Y |
| Citation(s) |
37505697 |
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| Submission date |
May 16, 2023 |
| Last update date |
Sep 07, 2023 |
| Contact name |
Selma Pascale Snini |
| E-mail(s) |
selma.snini@toulouse-inp.fr
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| Organization name |
Chemical Engineering Laboratory
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| Street address |
Avenue Agrobiopole BP 32607
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| City |
Castanet – Tolosan |
| ZIP/Postal code |
31326 |
| Country |
France |
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| Platforms (1) |
| GPL28924 |
Agilent-085497 Penicillium expansum SurePrint G3 Custom GE microarray (Probe Name version) |
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| Samples (8)
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| GSM7359908 |
Mycelium, CFS, replicate2 |
| GSM7359909 |
Mycelium, CFS, replicate3 |
| GSM7359910 |
Mycelium, CTRL, replicate3 |
| GSM7359911 |
Mycelium, CFS, replicate4 |
| GSM7359912 |
Mycelium, CTRL, replicate4 |
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| Relations |
| BioProject |
PRJNA973006 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE232607_RAW.tar |
78.6 Mb |
(http)(custom) |
TAR (of TXT) |
| Processed data included within Sample table |
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